Cellular defect found in inherited and sporadic ALS

August 10, 2021

Cellular defect found in inherited and sporadic ALS

At a Glance

  • In lab-grown neurons derived from people with inherited or sporadic ALS, buildup of a protein called CHMP7 in the nucleus led to cellular damage.
  • Using a drug to block this buildup prevented damage, suggesting a strategy to treat both inherited and sporadic ALS.